Biofilm and general contamination pose a challenge in pharmaceutical pure water systems. This accumulation of microorganisms forms a protective layer of organic polymers. The biofilm contains a variety of microorganisms, bacteria, and spores, including potential pathogens. They form in places where water and carbon meet solid surfaces, with microorganisms colonising the interfaces and forming complex communities. These microbes with their protective layer are a source of constant contamination and are resistant to regular rinsing with water.
Controlling biofilms
As an ideal breeding ground for pathogenic substances, biofilms can quickly become a critical hygiene problem in a water system, especially when aided by factors such as microbial inputs, temperature, and nutrient availability. If individual microbial structures of pathogenic species enter the water system, build a biofilm, or colonise an existing biofilm, the biofilm can serve as a habitat for all sorts of species with pathogenic potential.
Our approach
The removal of biofilm is a challenging task that requires a thorough and careful approach. Our special cleaning procedure includes several phases: Alkaline cleaning to remove the protective layer of biofilm, disinfection and actual removal of the biofilm, followed by passivation of the surface with hydrogen peroxide, which has an additional disinfecting effect. We rely exclusively on "clean" GMP-compliant chemicals and ensure that all process parameters are strictly observed during this sensitive treatment.